AI-powered eGFR Estimated Glomerular Filtration Rate
What Is eGFR and Why Does It Matter for Indians With Diabetes or Hypertension
eGFR stands for Estimated Glomerular Filtration Rate — a number calculated from your serum creatinine that tells you how well your kidneys are filtering your blood. A normal eGFR is 90 or above. Below 60 for three months or more means Chronic Kidney Disease. Below 15 means kidney failure. In India, diabetes and hypertension are the two leading causes of CKD — and most patients have no idea their kidneys are under stress until the damage is already significant. A simple serum creatinine test — available at any pathology lab for under ₹100 — is all you need to calculate your eGFR and know exactly where your kidneys stand today.
Why This eGFR Calculator Is Different From Others Available Online
Most online eGFR calculators use the older MDRD equation, which is less accurate at higher eGFR values and tends to underestimate kidney function in healthy patients. This calculator uses the CKD-EPI 2021 equation — the current international gold standard recommended by KDIGO 2022 guidelines — which is more accurate across all eGFR ranges and does not use race as a variable, making it fully applicable to Indian patients. It also includes urine ACR (Albumin-to-Creatinine Ratio) for complete CKD staging, creatinine trend analysis, a drug safety guide showing which common medications are dangerous at your eGFR level, and clinical flags for diabetes, hypertension, and NSAID use — the three biggest kidney destroyers in India.
The Drug Safety Guide — Why This Feature Could Protect Your Kidneys Right Now
One of the most dangerous and least discussed causes of kidney damage in India is medication. Ibuprofen, Diclofenac, and Nimesulide — sold over the counter at every medical shop in India — are NSAIDs that directly reduce blood flow to the kidneys. In a patient with already-reduced kidney function, a single course of these painkillers can cause a measurable drop in eGFR. Contrast dye used in angiograms and CT scans carries similar risk. This calculator includes a drug safety guide that tells you — based on your specific eGFR — which medications are safe, which require dose adjustment, and which should be avoided entirely. No other free eGFR calculator in India provides this.
eGFR, CKD and Fasting — What Your Nephrologist Has Not Told You
Chronic Kidney Disease is almost never a kidney-only problem. In over 80% of CKD cases in India, the underlying driver is metabolic — either Type 2 Diabetes causing diabetic nephropathy, or hypertension causing hypertensive nephropathy, or both. Both of these conditions share a common upstream cause: insulin resistance and chronic metabolic inflammation. Strategic fasting — when properly calibrated for kidney patients — is one of the most powerful interventions available for slowing CKD progression. By reducing insulin levels, fasting reduces the hyperfiltration pressure on the kidneys’ glomeruli, lowers systemic inflammation, improves blood sugar control, and reduces the metabolic load on already-stressed kidney tissue. The Metabolic Disease Protocol is specifically designed for patients with CKD, T2D, fatty liver and cardiovascular disease — with fasting protocols adjusted for kidney function constraints.
Frequently Asked Questions About eGFR and Kidney Function
Q: What is a normal eGFR level?
A: A normal eGFR is 90 mL/min or above (CKD Stage G1). Between 60–89 is mildly decreased (G2). Between 45–59 is mild to moderate decrease (G3a). Between 30–44 is moderate to severe decrease (G3b). Between 15–29 is severely decreased (G4). Below 15 is kidney failure (G5) requiring dialysis planning.
Q: What serum creatinine level indicates kidney disease?
A: Serum creatinine above 1.2 mg/dL in women and above 1.4 mg/dL in men generally suggests reduced kidney function — but the exact eGFR depends on age, sex and body size. A young muscular man with creatinine of 1.4 may have normal eGFR. An elderly woman with creatinine of 1.1 may already have CKD Stage 3. Always calculate eGFR rather than relying on creatinine alone.
Q: Can kidney function improve with diet and fasting?
A: In early-stage CKD (G1 to G3a), meaningful improvement in eGFR is documented and achievable with the right dietary and fasting protocol. In later stages (G3b to G4), the goal shifts to slowing progression and protecting remaining function. Strategic fasting reduces insulin-driven hyperfiltration pressure on the kidneys, lowers blood sugar, and reduces systemic inflammation — all of which slow CKD progression measurably.
Q: Which medicines are dangerous for kidney patients?
A: NSAIDs (Ibuprofen, Diclofenac, Nimesulide), contrast dye used in angiograms and CT scans, certain antibiotics (Gentamicin, Vancomycin), and high-dose Metformin in advanced CKD are the most common kidney-damaging medications in India. This calculator’s drug safety guide shows what is safe at your specific eGFR level.
Q: How often should I check my eGFR?
A: If you have diabetes or hypertension — once every 6 months. If your eGFR is between 30–59 (Stage G3) — every 3 months. If your eGFR is below 30 (Stage G4) — monthly, under specialist supervision.
eGFR Calculator — Kidney Function
CKD-EPI 2021 Equation · KDIGO 2022 CKD Staging · Drug Safety Guide
Please enter valid age (18+) and serum creatinine (0.1 to 20 mg/dL).
| Stage | eGFR | Description | Monitoring |
|---|---|---|---|
| G1 | ≥ 90 | Normal / High | Annually if at risk |
| G2 | 60 – 89 | Mildly decreased | Annually |
| G3a | 45 – 59 | Mild to moderate decrease | Every 6 months |
| G3b | 30 – 44 | Moderate to severe decrease | Every 3 months |
| G4 | 15 – 29 | Severely decreased | Monthly |
| G5 | < 15 | Kidney failure | Dialysis planning |